MTOR

The MTOR gene encodes for the mechanistic target of the protein rapamycin, also known as MTOR.

MTOR regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. The MTOR signaling pathway senses and integrates a variety of environmental cues to regulate growth and homeostasis. The pathway regulates many major cellular processes and is implicated in an increasing number of pathological conditions, including cancer, obesity, type 2 diabetes, and neurodegeneration.

It is hypothesized that some dietary regimes, like caloric restriction and methionine restriction, cause lifespan extension by decreasing MTOR activity. MTOR has important effects on 'autophagy' the process by which cells remove debris, and the failure of autophagy is thought to be one of the main reasons for the accumulation of cell damage and aging.

There are only nutrient cofactors that are known to inhibit MTOR activity such as curcumin, resveratrol, epigallocatechin gallate (EGCG), genistein, 3, 3-diindolylmethane (DIM), caffeine, D3 and omega 3 fatty acids. 

To determine your genotype for MTOR, you can test via GENOMIC INSIGHT.