DNA | Diet



Have you ever followed a diet to the letter and not seen the benefits? The answer to that question is probably yes, as everybody is different, and there is no universal diet that works for everyone.

One of the first products of its kind in the world, DNA | Diet is a test designed to help you manage your weight in a healthy and effective way under the supervision of your healthcare practitioner. It does this by giving you and your healthcare practitioner the information you need to design a personalised weight management plan based on your genetic makeup.

Your genes offer valuable information about how your body reacts to carbohydrates, saturated fats and intensity of exercise, allowing for extreme personalisation of your eating plan to suit your needs.

DNA | Diet tests several well-researched gene variations that impact metabolism, absorption and storage of fats and carbohydrates, as well as eating behaviour. Research shows that everyone responds differently to different food combinations and there isn’t one correct way of eating for everyone.

With the information gleaned from your DNA | Diet test, you can understand how your body will respond to the three most effective healthy eating plans. i.e. Low Fat, Mediterranean, and Low Carbohydrate. Once we have your results, we will provide a detailed report with recommendations that include dietary changes and an exercise programme.

The benefit of ordering this test from MY DNA CHOICES.

The feedback session is included in the cost of the test.

Benefits | Features

  • Provides strategies for weight management based on genetic makeup
  • Provides motivation for people looking to lose weight
  • Provides an understanding of why previous weight-management programs may have been unsuccessful
  • Provides insight into which diet type (i.e. Mediterranean style, Low Carbohydrate, Low Fat diet) may be most suited to you, based on your genotype 

Genes tested

Absorption and Metabolism

  • FABP2:  Influences fat absorption and metabolism.


  • PPARG: Involved in adipocyte differentiation. It is a transcription factor activated by fatty acids and is also involved in the regulation of glucose and lipid metabolism.
  • ADRB2: Involved in the mobilisation of fat from fat cells for energy, in response to catecholamines.
  • APOA5: Plays an important role in the regulation of plasma triglycerides.
  • ADIPOQ: This gene encodes adiponectin, which is expressed in adipose (fat) tissue. It plays a role in the modulation of a number of metabolic processes, including glucose regulation and fatty acid oxidation. 

Energy Homeostasis

  • UCP1: This gene plays a role in an individual's ability to burn fat.
  • UCP2: This gene plays a role in an individual's ability to maintain a healthy BMI.
  • UCP3: This gene plays a role in an individual's ability to maintain a healthy BMI.

Carbohydrate Responsiveness

  • ADRB2: This gene plays a role in the mobilisation of fat from fat cells for energy.
  • TAS1R2: Believed to contribute to the interindividual variation in sugar consumption.
  • SLC2A2 (GLUT2): Influences the first step in glucose-induced insulin secretion, affecting both food intake and regulation.
  • DRD2: Midbrain dopamine circuits may play an important role in both addiction and normal eating behaviour as they are involved in reward processing, particularly dopaminergic signalling via dopamine receptor 2 (DRD2).

Fat Metabolism, Obesity and Satiety

  • APOA2: An abundant apolipoprotein in HDL. Plays a complex role in lipoprotein metabolism, insulin resistance, obesity and atherosclerosis susceptibility.

Regulation of Metabolism and Feeding Behaviour

  • MC4R: A strong obesity candidate gene, significantly associated with energy intake and expenditure.

Regulation of Energy Intake

  • FTO: Involved in the regulation of arousal, appetite, temperature, autonomic function and endocrine system.
  • TCF7L2: Regulates blood glucose homoeostasis, influencing both insulin secretion and sensitivity.

Exercise Responsiveness

  • ADBR3: Involved in the regulation of lipolysis that influences metabolism.

Circadian Rhythms

  • CLOCK: An essential regulatory arm of the biological clock, involved in metabolic regulation.

Fat Storage

  • PLIN: Influences diet-induced obesity.


  • TNF-A: TNFα is a pro-inflammatory cytokine, secreted by both macrophages and adipocytes, which has been shown to alter whole-body glucose homoeostasis, and has been implicated in the development of obesity, obesity-related insulin resistance and dyslipidemia.

Pair with these biochemistry tests

Order these test to track and measure whether your genetic variations are manifesting in real-time:

Tests for

DNA | Diet: Gene variations associated with diet, exercise, weight management, metabolism, insulin sensitivity, satiety and feeding behaviour.

Sample type

Buccal (cheek) lining swab

Average processing time

14 - 21 days


Your DNA holds a wealth of invaluable information about your health and can tell you everything from whether you’re lactose intolerant to if you are at risk for potential DNA damage. Knowing how useful this can be this, we believe we should all have intimate knowledge of our unique genetic makeup. 

We believe that more medical info can be more useful than less. Combining our genetic tests to best suit your needs gives you more info in one go, plus works out more cost effective than doing the individual panels.

Armed with this invaluable information, you can begin to eliminate future health risks by carefully planning a personalised life-long diet, exercise, supplement and general well-being plan that works to prevent the diseases to which you most are susceptible.