Addictive behaviour can manifest in a number of disorders, which are complex in their aetiology and are influenced by both genetic and environmental factors. Genetics and addictive areas of the association include behavioural disorders such as eating disorders (binge eating), ‘adrenaline seeking’, and risk-taking behaviour. Substance use disorders include risk of alcohol, nicotine, cannabis and opioid dependence. This area will also report on psychosis response from cannabis use.
The genes associated with addictive behaviours are CHRNA3, CHRNA5, CNR1, FAAH, AKT1, DRD1, DRD2, DRD3, DRD4, COMT, OPRM1, BDNF, SLC6A4 and GABRA2. These genes are involved in cell signalling, endocannabinoid, dopaminergic, neurotrophic, serotonergic and stress response processes.
Benefits of DNA | MIND
Neuropsychiatric disorders account for up to 25% of all disability-adjusted life years (Gatt et al 2015.). Whilst the heritability of these mental disorders is significant, environmental factors also play a key role in their etiology. Genetic variations involved in key biological processes that contribute toward the risk of development of mental health disorders may give insights to the prevention, diagnosis and treatment of the disease.
The DNA Mind test analyses 30 genes which have been shown to have significant associations with key mental health disorders.
Key areas tests
Genes included in the test are involved in key biological areas related to mental health, these include:
- Lipid metabolism
- Neurotrophic, dopaminergic and serotonergic pathways
- Endo-cannabinoid pathway
Your DNA | MIND results
Once your DNA | MIND cheek swab has been returned to the lab for analysis, and your test analysis in the lab, the results will be sent to you. We encourage you to discuss your results with your doctor so they can plan a safe, informed and effective treatment plan for you.
Note: If your medical practitioner isn’t willing to assist in the process, you should consider getting a second opinion. You have the right to choose a medical practitioner willing to accommodate your unique healthcare needs. We can recommend health care practitioners trained in this test if need be.
It may sound like something out of a sci-fi movie, but genetic testing is a powerful health tool that can give you a deep understanding of how your body works.
At the heart of it is the molecule DNA. Every single cell in our bodies – from our heart to skin, blood and bone – contains a complete set of our DNA. This powerful molecule carries our genetic code and determines all manner of traits, from our eye colour to aspects of our personalities and, of course, our health. Interestingly, 99.9% of the DNA from two people is identical. It’s the other 0.1% of DNA code sequences that make us unique.
What are genes
Genes are segments of DNA that contain the instructions your body needs to make each of the many thousands of proteins required for life. Each gene is comprised of thousands of combinations of ‘letters’ which make up your genetic code. The code gives the instructions to make the proteins required for proper development and function.
What are gene variations
An example of a genetic variation is that one ‘letter’ may be replaced by another. These variations can lead to changes in the resulting proteins being made. For example, a ‘C’ may be changed to a ‘G’ at a point in the genetic code. When the variation affects only one genetic ‘letter’ it is called a Single Nucleotide Polymorphism, or SNP (pronounced “snip”). Variations can however also affect more than one ‘letter’. Genetic tests look at specific chromosomes, genes or proteins, and the variations that occur within them, to make observations about disease or disease risk, body processes or physical traits.
Are gene variations bad
In general, variations should not be considered good or bad. Rather, genetic variations are simply slight differences in the genetic code. The key is to know which form of the variation you carry so that you can make appropriate lifestyle choices. And that is the beauty of genetic testing. It can tell you more about the way you're built so that you can tailor your lifestyle to fit your biology.
Buccal (cheek) lining swab
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