DNA | Medcheck



Medcheck is made up of three separate test panels:

  • Medcheck cardio
  • Medcheck pain
  • Medcheck psych

The MyGeneRx test analyses your unique DNA to determine how you metabolise common cardiovascular, pain and psychiatric medications.

You can decide to do each panel separately or all 3 at once. Our combo tests always workout better value.

What is 'pharmacogenomics'?

Pharmacogenomics, the study of the relationship between genes and response to drugs, has been the subject of intensive research over the past two decades and robust evidence now exists to support testing under clinical conditions.

There is a great deal of variability in how someone responds to medications due to their genes that govern drug metabolism. Pharmacogenomics empowers your doctor to provide person-specific medical interventions and replaces the current trial and error approach to drug therapy.

A Pharmacogenomics test gives insight into how specific prescription drugs are metabolised, transported, and bound in your body. This, in turn, allows your doctor to prescribe those medications that will most likely be effective, to avoid those that will not, and to better adjust medication doses to safe, yet therapeutic, levels. Such a personalised approach to medicine has the power to produce better results, particularly for individuals whose genetic profile puts them at risk of experiencing either treatment failure or an adverse reaction from a given drug.

We believe that more medical info can be far more useful than less. Combining our genetic tests to best suit your needs gives you more info in one go plus works out more cost-effective than doing individual panels.

The benefit of ordering this test from MY DNA CHOICES.

The feedback session is included in the cost of the test.

This test looks at

Gene variations associated with the metabolism (breakdown) of common cardiovascular, pain and psychiatric medications (listed in the sample report below).

Benefits | Features

  • With a deeper knowledge of your genetics, you can ensure you’re taking the right medication, at the right dose
  • This means fewer side-effects, safer treatment, and maximum efficacy
  • Medcheck Cardio


    Analyses genetic variants linked to the metabolism of common cardiovascular medications such as:

    • Angiotensin II receptor antagonists
    • Antianginal agents
    • Antiarrhythmics
    • Anticoagulants
    • Antiplatelets
    • Beta-blockers
    • Diuretics
    • Statins

    Medcheck Pain


    Analyses genetic variants linked to the metabolism of common pain medications such as:

    • Fibromyalgia Agents
    • Muscle Relaxants
    • NSAID's
    • Opioids  

    Medcheck Psych


    Analyses genetic variants linked to the metabolism of common psychotropic (psychiatry) medications such as:

    • Anti-addictives
    • Anti-ADHD agents
    • Anticonvulsants
    • Antidementia agents
    • Antidepressants
    • Antipsychotics
    • Benzodiazepines
    • Mood stabilizers

    Genes tested

    Genes tested in the MyGeneRx test
    ABCG2 421 C>A
    ADRA2A -1291 C>G
    ANKK1/DRD2 Taq1A
    BDNF 434 C>T
    COMT Val158Met
    CYP1A2 *1F, *1K
    CYP2B6 *16, *6, *9, *11,*18
    CYP2C19 *2, *3, *4, *4B, *6, *7, *8, *9, *10, *17
    CYP2C9 *2, *3, *4, *5, *6, *8, *11, *27
    CYP2D6 *2, *3, *4, *4M, *6, *7, *8, *9, *10, *12, *14A, *14B, *17, *29, *35, *41, *5 (gene deletion), XN (gene duplication)
    CYP3A4 *3, *12, *17, *22
    CYP3A5 *3, *3C, *6, *7
    Factor II 20210 G>A
    Factor V Leiden 1691 G>A
    MTHFR 677 C>T, 1298 A>C
    OPRM1 A118G
    SLCO1B1 521T>C
    UGT2B15 *2
    VKORC1 -1639 G>A

    Sample required 

    Buccal (cheek) lining swab - this is just a simple, painless firm rub with a long earbud (the swab) on the inside of your cheek. 

    Processing time 

    Around 14 working days

    Test sample report

    The results

    Once your results are ready, your report will be sent to you. We encourage you to discuss your results with your doctor so they can plan a safe, informed and effective treatment plan for you.


    If your medical practitioner hasn't been trained to work with this test, please contact us. We can arrange for the lab to contact your doctor and detail them. Please email Dr Heidi on info@joincircles.com