The ADIPOQ gene encodes adiponectin, which is expressed in adipose (fat) tissue. It plays a role in the modulation of a number of metabolic processes, including glucose regulation and fatty acid oxidation.
This SNP has been associated with many obesity-related traits including insulin resistance, weight, BMI, and waist: hip circumferences. The association between the −11391 G>A polymorphism and insulin resistance appears to be dependent on BMI, suggesting that the influence of this gene variant on glucose homeostasis may be dependent on body fatness.
If you carry the G - allele and are overweight, then you are predisposed for an increased risk for insulin resistance and metabolic syndrome.
If you carry the A - allele, then you may be predisposed to higher adiponectin levels, lower weight and decreased susceptibility to insulin resistance.