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GSTO2 (Glutathione S-Transferase Omega 2) is a protein-coding gene. Among its related pathways are the metabolism of water-soluble vitamins and cofactors, glutathione conjugation, and drug metabolism via cytochrome P450.

Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens.

Genetic variations in this gene have been associated with an increased risk for breast cancer and cellular damage. Please check your genetic variation in GPX1 and GPX4 as GSTO2 and GPX have a co-expression relationship.