This HTR1A gene encodes a G protein-coupled receptor for serotonin (5-hydroxytryptamine) and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene results in behavior consistent with an increased anxiety and stress response. A genetic variation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.
The G-allele is associated with depression and therefore it is important to discuss this with your doctor and to make healthy choices that support healthy serotonin levels.
When looking at your genotype for this gene, it is a good idea to look at the other "mood" genes such as to determine your overall genetic predisposition for depression and mood problems.