The OPRM1 gene encodes the mu receptor by a substance such as morphine causes sedation, euphoria and decreased respiration.
Individual differences in the function of the mu-receptor system predict personality traits that confer vulnerability to or resiliency against risky behaviors such as the predisposition to develop substance use disorders. Activating opioid receptors can promote eating and weight gain, at least in the short term.
There are several ways to increase opioid activity. All of these give us a positive feeling, and at least some of it is because of the opioid system in our body. The following either increase activation of our mu opioid receptors, increase endorphins, reduce stress and anxiety, which naturally activate our mu-opioid receptors, or make our receptors more sensitive.
If you carry the AG -allele in this gene, then you may be predisposed to increased cortisol response to psychosocial stress.
- High-intensity exercise
- Sun | UVB
- Warm showers
- Social interaction
- Foods high in butyrate
- Capsaicin | Chilli
- Probiotic high in acidophilus