SUOX

The SUOX gene provides instructions for making an enzyme called sulfite oxidase, which helps break down protein building blocks (amino acids) that contain sulfur when they are no longer needed. Specifically, sulfite oxidase is involved in the final step of this process, in which sulfur-containing molecules called sulfites are converted to other molecules called sulfates by adding an oxygen atom (a process called oxidation).

The GG-allele is the risk genotype and is associated with a slower conversion of sulfites
 to 
sulfates. Sulfites
 can
 inhibit
 tyrosinase, polyphenol oxidase





 
and
 ascorbate
oxidase and this
 can
 affect
 dopamine
 levels.  Sulfites 
can
 decrease 
ATP, deplete
 glutathione, sensitivity
 can 
lead 
to 
asthma and
 low 
blood
 sugar.

Sulfite 
oxidase 
is 
inhibited 
by 
heavy
 metals and 
low
 molybdenum. Severe
 B12
deficiency 
decreases
 SUOX
 activity.