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Toll-like receptors play a role in recognizing pathogens and activating the innate immune response. The TLR4 protein recognizes LPS (lipopolysaccharide, a component of gram-negative bacteria), as well as viral and internal proteins.

If you have excess TLR4 activation, the following Inhibit TLR4: Resveratrol, grape seed extract, AHCC, tea polyphenols/jasmine tea, quercetin, garlic, EGCG, berberine, cinnamon/cinnamaldehyde, curcumin, ginkgo, licorice, and walnut.