The report investigates 24 genes that affect health and wellbeing categorised into our 8 Pillars of Health & Wellbeing below. The report also comes with a supplementary 20-page Nutrition & Lifestyle Guide to help you better understand and follow the personalised advice and information given in the report.
The 8 Pillars of Health & Wellbeing:
Digestion - Gluten and lactose intolerance, serotonin sensitivity
Metabolism - Insulin secretion, increased appetite, weight gain and loss, obesity and type 2 diabetes risk
Stress - Ability to cope with stress, pain tolerance, cortisol (stress hormone) regulation, blood pressure, and electrolyte balance
Nutrients - Need for and ability to metabolise folate (impacting methylation), protein, carbohydrate and fats, omega-3, vitamin B12, and vitamin D
Stimulants - Caffeine sensitivity, alcohol metabolism, the impact of adenosine
Immunity - Susceptibility to increased inflammation, histamine intolerance
Exercise - Power vs endurance, injury risk, recovery
Sleep - Circadian rhythms, early bird/night owl, melatonin receptivity
DNA is your body’s instruction manual, controlling every single function from when you were only made up of a few cells, until now. It looks like a twisted ladder, made up of two halves - you inherit one half from your mother, the other from your father. This combination is what makes you, you.
Each ‘rung’ of the ladder contains two ‘letters’ of DNA code called nucleotides which bond together in pairs: A (adenine) and T (thymine) bond together, as do C (cytosine) and G (guanine).
Genes are portions of the ladder which use combinations of the nucleotide code to perform specific functions.
Over time, due to environmental and lifestyle factors, minor changes called single nucleotide polymorphisms (SNPs) occur in the DNA code and are passed down from parent to child, from generation to generation. Remember the nucleotides? Well, a C might be replaced by a T, changing the instructions given to a gene.
Some changes are positive, making us stronger and more resilient (like being able to digest milk after infancy), some negative (like being likely to store more fat as a result of past famine or food shortage) and some make no difference at all. SNPs can be passed down on just one side of your ladder, from one parent, or from both, enhancing the effect.
SNPs are generally what we are looking for when we test your DNA.