SPM Active


Specialized Pro-resolving Mediators

SPM Active is a revolutionary nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil. Designed to support the body’s natural capacity to respond to physical challenges and resolve physical stress.

Benefits | Features

  • A breakthrough in tissue health and immune response support
  • Supports healthy immune cell (i.e., macrophage) resolution-related activities 


  • Gluten-free
  • Non-GMO
  • Packaged in glass and/or recyclable material


30 and 60 Softgels
Serving Size: 2 Softgels
Servings per container: 15 or 30

Amount per 2 softgels:

Ingredient Amount Daily Value
Calories from Fat  
Total Fat 0.5 g  <1%* 
Cholesterol <5 mg  <2%* 
Active Portion of Fractionated Marine Lipid Concentrate† 500 mg  ** 
SPM content standardized to    
18-hydroxy-eicosapentaenoic acid (18-HEPE) and    
17-hydroxy-docosahexaenoic acid (17-HDHA)    Patent pending 

*Percent Daily Values are based on a 2,000 calorie diet
**Daily Value not established

Patent pending

Other Ingredients

Fractionated marine lipid concentrate [(anchovy and sardine oil, and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, water, pectin, and sorbitol), and lemon oil. Contains: Fish (anchovy and sardine)


Take two softgels once daily or as directed by your healthcare practitioner.

Cautions | Warnings | Interactions

Consult your healthcare practitioner before use. Do not exceed recommended dosages unless on the advice of a healthcare provider. If you are on medication, taking nutritional supplements, suffering from any medical condition, pregnant, or breastfeeding, it is advisable to seek medical advice before starting any new food, supplement or remedy. Do not use this product if you are allergic to any of the ingredients. Keep out of the reach of children. 


Store tightly closed in a cool, dry, dark place.