PPARGC1A

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This gene plays an essential role in energy regulation and is expressed in tissues that have high energy demands and is, therefore, abundant in mitochondria and associated with an aerobic activity.

Sometimes called the master regulator of mitochondria, PPARGC1A is also involved in the exercise-induced increase in mitochondria.

If you have a medium to high impact in this gene, you can upregulate it with the correct food plan, calorie restriction and increase exercise.