SULT1A1

The SULT1A1 gene encodes for the Sulfotransferase Enzymes Catalyze, the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. This gene is broadly expressed in the duodenum, liver, and 22 other tissues. It plays an important role in the detoxification of endogenous and exogenous compounds e.g. Tamoxifen. 

SULT1A1 is involved in the inactivation of estrogens and bioactivation of heterocyclic amines which form when meat, poultry, and seafood are cooked at a high temperature. Frying, broiling, and grilling produce the largest amounts of these compounds, and polycyclic aromatic hydrocarbons ( a group of more than 100 different chemicals that are released from burning coal, oil, gasoline, trash, tobacco, wood, or other organic substances such as charcoal-broiled meat).

Medium to high genetic variations in this gene can result in a slower pathway. Therefore it is important to provide nutritional support for this phase 2 liver pathway as well as avoid making toxic, environmental choices. 

If you think your diet is lacking sulphur, you could "add-in" a supplement that contains MSM (methylsulfonylmethane), sulphur-rich supplements (e.g. alpha-lipoic acid) or glutathione.